Bulent Atalay presents an illustrated lecture on Leonardo da Vinci's multifaceted interests as artist and scientist. The lecture is based on his recently released book, 'Math and the Mona Lisa: The Art and Science of Leonardo da Vinci' (Smithsonian Books). The most significant message of the book is precisely Leonardo's own modus operandi: "It is important to be curious, it is important to explore different intellectual worlds, but it is essential to seek their connections."