Fifty Years of Computational Biology

The lecture will survey the field of theoretical structural biology as it has developed since the prediction of the alpha-helix structure by Linus Pauling in 1951 and DNA by Crick and Watson in 1952. Topics: predictive modeling and simulation of molecules as 3-D objects; protein molding—the process of self-assembly in which protein molecules organize into precise nano-machines; and bio-informatics with attention to classification of protein structures.