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CATEGORIES:Lecture/Presentation/Talk
DESCRIPTION:Join us at Gunn Rotunda in the Stanford Neurosciences Building 
 to learn about the latest cutting-edge\, cross-disciplinary brain research\
 , from biochemistry to behavior and beyond\n\n\nJoin the speaker for coffee
 \, cookies\, and conversation before the talk\, starting at 11:45am.\n\nMor
 e than rewarding: how do sound and light cues impact risky decision making 
 and motor impulsivity?\n\nAbstract\n\nIt has long been known that audiovisu
 al cues\, when paired repeatedly with appetitive outcomes like sugary rewar
 ds or liquids\, can come to act as reinforcers in their own right due to th
 e attribution of incentive salience. Electronic gambling machines and gamin
 g apps make heavy use of these cues to signal rewarding events during play.
  We have shown that\, in both rats and humans\, presenting sound and light 
 cues concurrent with reward delivery can increase preference for “high-risk
 \, high-reward” options in laboratory-based gambling tasks. However\, compu
 tational modeling using reinforcement learning algorithms suggest that cue-
 induced risky choice is not driven by enhanced learning from rewards\, as w
 e would expect if the cues were acting as conditioned reinforcers\, but ins
 tead through impaired learning from penalties. Furthermore\, analyses of da
 ta from nearly 700 rats suggest that even though the risk-promoting effect 
 of the cues looks superficially similar across sex\, cue-induced risky choi
 ce may operate via different cognitive processes in females vs males. Data 
 from behavioral pharmacology studies and chemogenetic manipulations suggest
  reward-concurrent cues alter the recruitment of multiple neurotransmitter 
 systems and brain regions in the decision-making process. Although daunting
  in its complexity\, these studies also suggest a variety of approaches tha
 t may neutralize the deleterious effect of such cues on cognition.\n\n \n\n
 Catharine Winstanley\, Ph.D.\n\nUniversity of British Coloumbia\n\nMy resea
 rch aims to understand the neurobiological regulation of impulsivity and af
 fective decision making\, with the goal of using this knowledge to improve 
 treatments for psychiatric disorders such as problem gambling and drug addi
 ction.\n\n(Visit lab website)\n\nHosted by - Leili Mortazavi (Deisseroth La
 b)\n\n \n\nAbout the Wu Tsai Neuro Seminar Series\n\nThe Wu Tsai Neuroscien
 ces Institute seminar series brings together the Stanford neuroscience comm
 unity to discuss cutting-edge\, cross-disciplinary brain research\, from bi
 ochemistry to behavior and beyond.\n\nTopics include new discoveries in fun
 damental neurobiology\; advances in human and translational neuroscience\; 
 insights from computational and theoretical neuroscience\; and the developm
 ent of novel research technologies and neuro-engineering breakthroughs.\n\n
 Unless otherwise noted\, seminars are held Thursdays at 12:00 noon PT.\n\nS
 ign up to learn about all our upcoming events
DTEND:20240502T200000Z
DTSTAMP:20260314T204048Z
DTSTART:20240502T190000Z
GEO:37.430178;-122.176478
LOCATION:Stanford Neurosciences Building\, Gunn Rotunda (E241)
SEQUENCE:0
SUMMARY:Catharine Winstanley - More than rewarding: how do sound and light 
 cues impact risky decision making and motor impulsivity?
UID:tag:localist.com\,2008:EventInstance_43714005460037
URL:https://events.stanford.edu/event/catharine_winstanley_-_more_than_rewa
 rding_how_do_sound_and_light_cues_impact_risky_decision_making_and_motor_im
 pulsivity
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