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Stanford Bio-X Frontiers in Interdisciplinary Biosciences Seminar, "Reinterpreting the Genetic Code - Engineering and Probing Protein Behavior with Non-Canonical Amino Acids"
Frontiers in Interdisciplinary Biosciences Seminar
Speaker: David Tirrell, CalTech
Seminar Title: "Reinterpreting the Genetic Code - Engineering and Probing Protein Behavior with Non-Canonical Amino Acids"
Hosted by: Dr. H. Tom Soh, Professor of Radiology and Electrical Engineering
The genetic code, elucidated in the 1960s through the work of Nirenberg, Ochoa, Khorana and their coworkers, provides a set of molecular instructions for translating nucleic acids into proteins. Through the efforts of our laboratory and others, the code has been “reinterpreted” in various ways to enable the participation of an expanded set of amino acids in cellular protein synthesis. These developments have provided a basis for powerful new approaches to protein design and to spatially and temporally resolved analysis of cellular processes.